Top Definition
When you're intoxicated from cigarettes and coffee
We were so damn niffed yesterday nigguh! We drank 2 cops of coffee and we smoked 3 cigarettes!
Por Bregysunnyboy 22 de febrero de 2011
1 more definition
Annoyed. Perturbed. Not as intense as Pissed. Usually directed towards a person
A: "Fine I was just trying to be nice I won't bother you again"
B: "What is that all about"
A: "Nothing"
B: " "I wont bother you again" you sound like you are niffed at me"
A: (Insert explanation)
Por Little Drummer Boy Fred 11 de julio de 2015

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