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1.
Achieve an erection; get a hard-on; by extension, perform any difficult task.
He's so asexual, he couldn't get it up at an Annie Sprinkle marathon.
Por Cornholio 04 de noviembre de 2003
 
2.
to get an erection.
to muster the energy.
Dude, you hear Jack tried to bang his chick last night, but couldn't get it up?

I can't get it up to go shopping today.
Por Ptorrens 10 de febrero de 2012
 
3.
when u get an erection or a boner in some senses. also means to not be circumcised or a jew.
i wish my mom would help me getitup but thats just wrong cuz im not getitup.
Por xhottbsx 07 de marzo de 2008