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1.
Slang term for something of big time, major, gigantic or huge proportions.
Hey baby, you got some major league hooters.
Por JohnstonGuy 20 de junio de 2005
 
2.
feces. crap. poop. bowel movement number 2.
Joe: Ah man i gotta take a major league!
Andy: You gotta league it?
Por lizzynicz 28 de mayo de 2009