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1.
The moment someone realizes that they got owned.
John felt he was up for the cinnamon challenge, but experienced plexus when he found that someone had replaced the cinnamon with cayenne pepper powder.
Por abradacabra 12 de febrero de 2010
 
2.
(noun) a confusing or badly written legal opinion or contract

origin: late 15th century (as the adjective perplexed): from the obsolete adjective perplex ‘bewildered’, from Latin perplexus 'entangled', based on plexus 'interwoven', from the verb plectere
this memorandum is utter plexus
Por Lord Wolff 02 de junio de 2011
 
3.
the back of the knee
Alex rubbed my plexus and i felt so good.
Por ur lover 24 de abril de 2006